Feedback
Composition : Human Albumin, 250 g/L (ALBUNORM 25%)
Availability : ALBUNORM 25%: botol 50 & 100 mL
Farmakologi: The physiological function of albumin is related to blood oncotic pressure and transport function. Albumin maintains the balance of circulating blood volume and transport of hormones, enzymes, drugs, and toxins
Indications: Restore and maintain circulating blood volume when fluid depletion (hypovolemia) occurs and colloids are required.
Contraindications: Hypersensitivity to albumin preparations or other additives
Dosage and Administration: The albumin concentration, dose, and infusion rate should be adjusted to the individual needs of the patient
Warnings and Cautions: If an allergic or anaphylactic reaction occurs, the infusion should be stopped immediately and appropriate treatment given. ALBUNORM should be used with caution in patients who are at risk for hypervolemia and/or hemodilution. Examples of these conditions are: decompensated cardiac insufficiency, hypertension, esophageal varices, pulmonary edema, hemorrhagic diathesis, severe anemia, renal and post-renal anuria.
Side Effects: Headache, flushing, allergic reactions, nausea, etc.
Drug Interactions: No specific interactions of human albumin with other medicinal products are known.
What is the function/role of ALBUNORM fluid?
ALBUNORM is a human albumin fluid that has physiological functions, especially its effect on blood oncotic pressure and transport function. Albumin maintains the balance of circulating blood volume and transport of hormones, enzymes, drugs and toxins. ALBUNORM is available in 25% concentration (hyperoncotic fluid).
What are the indications of ALBUNORM 25%?
ALBUNORM 25% is indicated for hypoalbuminemia (burns, nephrotic syndrome, etc.), albumin synthesis dysfunction (liver cirrhosis, etc.) and hemorrhagic shock. To improve and maintain circulating blood volume in volume-deficient states. The choice of albumin fluid depends on the patient's clinical situation and is based on agreed therapeutic recommendations.
Can ALBUNORM 25% be used for BPJS patients?
ALBUNORM 25% has entered the National Formulary. Based on the formulary, 25% ALBUNORM is for infants and children with albumin levels < 3 g/dL, and/or for perioperative cases, and/or for nephrotic syndrome, as well as in pre-shock or shock conditions, and/or for cases of ascites requiring massive/intense with compression of the respiratory or abdominal organs.
How is 25% ALBUNORM used for resuscitation?
For fluid resuscitation, the selection of the ALBUNORM solution used is adjusted to the patient's condition and clinical indications. However, in conditions where a rapid increase in blood pressure is required, 25% ALBUNORM solution (hyperoncotic solution) with crystalloid solution can be used to fill the interstitial spaces.
How is 25% ALBUNORM used for albumin correction?
Albumin correction is required in patients with hypoalbuminemia (burns, nephrotic syndrome, etc.), albumin synthesis dysfunction (liver cirrhosis, etc.) or hemorrhagic shock. Faster and more accurate albumin correction using 25% ALBUNORM.
What is the dosage for ALBUNORM 25% fluid?
The concentration of ALBUNORM preparations, dosages and infusion ranges are adjusted according to the needs of the individual patient. Meanwhile for ALBUNORM 25%, the dose is adjusted according to the patient's weight, age, and symptoms. Adequate circulating fluid measurements need to be made to determine the required dose.
How quickly can the 25% ALBUNORM fluid infusion be given?
The rate of infusion of ALBUNORM 25% is adjusted to the needs of each patient, namely based on conditions and clinical indications for giving ALBUNORM 25%. Normally, the recommended infusion rate of 25% ALBUNORM is 2-4 mL/min.
Can the administration of 25% ALBUNORM fluid be combined with other injection drugs?
Human albumin fluid should not be mixed with other drugs or other transfusion preparations
What are the reported side effects of ALBUNORM 25%?
Side effects of using 25% ALBUNORM fluid are relatively rare, such as hypotension, flushing, urticaria, nausea.
How long can 25% ALBUNORM be kept after opening? If it has been opened then closed again and saved can it still be used?
Recommended maximum 4 hours after opening. ALBUNORM 25% is recommended for single use. Beyond that, the stability data is unknown